Proton Pump Inhibitors (Nexium, Prevacid, Prilosec)

Proton pump inhibitor (PPI) drugs are used to treat heartburn and related symptoms such as indigestion, gastritis and acid reflux.  The major brands of these medications include Nexium, Prevacid, Prilosec.


Increased risk of Kidney disease and acute interstitial nephritis.

FDA Action

In December 2014, the packaging and labels of these medications was changed to include an association between PPIs and interstitial nephritis.

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